吳美滿(Wu, Meei-Maan) 助理教授

Email
mmwu@tmu.edu.tw
現   職
公共衛生學科 助理教授

學經歷

學 歷

畢業學校與學位[修業時間]
Johns Hopkins University公衛學院流行病學系 博士
1989/09~1996/05
國立臺灣大學公共衛生研究所 碩士
1982/09~1984/06
國立臺灣大學公共衛生學系 學士
1978/09~1982/06

本校學術經歷

任職單位與職稱[起迄時間]
公共衛生學科助理教授
2017/02/24~
公共衛生學系專案助理教授
2006/08/01~2007/12/31
公共衛生學系助理研究學者(計畫補助)
2003/08/01~2006/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
公共衛生學系助理教授
2020/01/01 ~
(舊)應用分子流行病學碩士學位學程助理教授
2018/04/01 ~

其它經歷

任職單位與職稱[起迄時間]
台灣大學博士後研究員
2008/01~2012/07
中央研究院生物醫學研究所博士後研究員
1996/11~2003/07
國立臺灣大學公衛所研究助理
1988/07~1989/07
中央研究院生物醫學研究所助研究員
1986/08~1988/06

專長與研究領域

學門領域
學術專長

論文著作

清冊下載


1. 2023 Phiri YVA,Wu MM,Chen YH,Zou ML,Jiang CB,Wu CD, Huang HC, Lung SCC, Chien LC, Lo YC, Lee FY, Chao HJ.. Environmental determinants of household microbial and allergen levels in the Greater Taipei Area. . Building Environ. .2023

2. 2023 Hong X,Hsieh MT,Tseng TY,Lin HY,Chang HC,Yau ST, Cheng WC, Ke B, Liao HH, Wu CY, Liu AA, Wu MM, Huang KY, Yang PC, Kuo SC, Hung MC*, Lee PC*. . Diarylheptanoid 35d overcomes EGFR TKI resistance by inducing hsp70-mediated lysosomal degradation of EGFR in EGFR-mutant lung adenocarcinoma. . J Biol Chem. .2023

3. 2022 Huang EJC,Sung FC,Hung PH,Muo CH,Wu MM,Yeh CC. The Association of Erythropoietin and Age-Related Macular Degeneration in Hemodialysis Patients: A Nationwide Population-Based Cohort Study. . Int J Mol Sci. .2022

4. 2022 Yu MZ,Wu MM,Chien HZ,Liao CT,Su MJ,Huang SF, Yeh CC. Risk Prediction Models for Patients with Head and Neck Cancer Among the Taiwanese Population. . Cancers. .2022

5. 2022 Wu MM,Chen CW,Chen CY,Lee CH,Chou M,Hsu LI, Lee TC, Chen CJ. TIMP3 Gene Polymorphisms of -1296 T > C and -915 A > G Increase the Susceptibility to Arsenic-Induced Skin Cancer: A Cohort Study and in Silico Analysis of Mutation Impacts . Int J Mol Sci. .2022

6. 2021 Wu CM,Su FH,Muo CH,Huang JC,Wu MM,Yeh CC. Analysis of different types of interferon-associated retinopathy in patients with chronic hepatitis C virus infection treated with pegylated interferon plus ribavirin . Viruses .2021 ;(13):475-475

7. 2021 Wu MM,Hsieh FI,Hsu LI,Lee TC,Chiou HY,Chen CJ. GT-Repeat Polymorphism in the HO-1 Gene Promoter Is Associated with Risk of Liver Cancer: A Follow-Up Study from Arseniasis-Endemic Areas in Taiwan. . Journal of Clinical Medicine .2021 ;(10):1489-1489

8. 2021 Yeh CC,Wu MM,Wu CM,Sung FC,Muo CH,Te A, Su FH. Increased risk of age-related macular degeneration with chronic hepatitis C virus infection: a nationwide population-based propensity score-matched cohort study in Taiwan. . Viruses .2021

9. 2019 Pidugu VK,Wu MM,Yen AH,Pidugu HB,Chang KW,Liu CJ, LeeTC. IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling . Oncogene .2019 ;(38):3232-3248

10. 2019 Pidugu VK,Pidugu HB,Wu MM,Liu CJ,Lee TC. Emerging functions of human IFIT proteins in cancer . Front in Mol Biosci. .2019 ;(6):148-148

11. 2017 Hsu LI,Hsieh FI,Wang YH,Lai TS,Wu MM,Chen CJ, Chiou HY, Hsu KH. Arsenic exposure from drinking water and the incidence of CKD in low to moderate exposed areas of Taiwan: a 14-year prospective study. . Am J Kidney Dis .2017 ;(70):787-797

12. 2017 Wu MM,Li CF,Lin LF,Wang AS,Pu YS,Wang HH, Mar AC, Chen CJ, Lee TC. Promoter Hypermethylation of LGALS4 Correlates with Poor Prognosis in Patients with Urothelial Carcinoma. . Oncotarget .2017 ;(8):23787-23802

13. 2016 Wu MM,Lee CH,Hsu LI,Cheng WF,Lee TC,Wang YH, Chiou HY, Chen CJ. Effect of heme oxygenase-1 gene promoter polymorphism on cancer risk by histological subtype: A prospective study in arseniasis-endemic areas in Taiwan . Int J Cancer .2016 ;(138):1875-1886

14. 2016 Hsu LI,Cheng YW,Chen CJ,Wu MM,Hsu KH,Chiou HY, Lee CH. Cumulative arsenic exposure is associated with fungal infections: two cohort studies based on southwestern and northeastern basins in Taiwan. . Environ Int .2016 ;(96):173-179

15. 2016 Hsu LI,Wang YH,Hsieh FI,Yang TY,Jeng RWJ,Liu CT, Chen CL, Hsu KH, Chiou HY, Wu MM, Chen CJ. Effects of Arsenic in Drinking Water on Risk of Hepatitis or Cirrhosis in Persons With and Without Chronic Viral Hepatitis . Clin Gastroenterol Hepatol .2016 ;(14):1347-1355

16. 2015 Hsu LI,Wu MM,Wang YH,Lee CY,Yang TY,Hsiao BY, Chen CJ. Association of Environmental Arsenic Exposure, Genetic Polymorphisms of Susceptible Genes, and Skin Cancers in Taiwan . Biomed Res Int .2015 ;(2015):892579

17. 2014 Wu MM,Chen HC,Chen CL,You SL,Cheng WF,Chen CA, Lee TC, Chen CJ. A prospective study of gynecological cancer risk in relation to adiposity factors: cumulative incidence and association with plasma adipokine levels . PLoS One .2014 ;(9):104630

18. 2014 Yang TY,Hsu LI,Chiu AW,Pu YS,Wang SH,Liao YT, Wu MM, Wang YH, Chang CH, Lee TC, Chen CJ. Comparison of genome-wide DNA methylation in urothelial carcinomas of patients with and without arsenic exposure. . Environ Res .2014 ;(128):57-63

19. 2014 Wang HH,Wu MM,Chan MW,Pu YS,Chen CJ,Lee TC. Long-term low-dose exposure of human urothelial cells to sodium arsenite activates lipocalin-2 via promoter hypomethylation. . Arch Toxicol .2014 ;(88):1549-1559

20. 2013 Hsu LI,Chen GS,Lee CH,Yang TY,Chen YH,Wang YH, Hsueh YM, Chiou HY, Wu MM, Chen CJ. Use of arsenic-induced palmoplantar hyperkeratosis and skin cancers to predict risk of subsequent internal malignancy. . Am J Epidemiol .2013 ;(177):202-212

21. 2013 Chiang YC,Chang MC,Chen PJ,Wu MM,Hsieh CY,Cheng WF, Chen CA. Epigenetic silencing of BLU through interfering apoptosis results in chemoresistance and poor prognosis of ovarian serous carcinoma patients. . Endocr Relat Cancer .2013 ;(20):213-227

22. 2013 Chung CJ,Huang YL,Huang YK,Wu MM,Chen SY,Hsueh YM, Chen CJ. Urinary arsenic profiles and the risks of cancer mortality: a population-based 20-year follow-up study in arseniasis-endemic areas in Taiwan. . Environ Res .2013 ;(122):25-30

23. 2013 Wang YH,Yeh SD,Wu MM,Liu CT,Shen CH,Shen KH, Pu YS, Hsu LI, Chiou HY, Chen CJ. Comparing the joint effect of arsenic exposure, cigarette smoking and risk genotypes of vascular endothelial growth factor on upper urinary tract urothelial carcinoma and bladder cancer . J Hazard Mater .2013 ;(262):1139-1146

24. 2011 Hsieh YC,Lien LM,Chung WT,Hsieh FI,Hsieh PF,Wu MM, Tseng HP, Chiou HY, Chen CJ. Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes . Environ Res .2011

25. 2011 Hsu LI,Chen WP,Yang TY,Chen YH,Lo WC,Wang YH, Liao YT, Hsueh YM, Chiou HY, Wu MM, Chen CJ. Genetic polymorphisms in glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of southwestern Taiwan . J Biomed Sci .2011

26. 2011 Wu MM,Chiou HY,Chen CL,Hsu LI,Lien LM,Wang CH, Hsieh YC, Wang YH, Hsueh YM, Lee TC, Chen WF, Chen CJ. Association of heme oxygenase-1 GT-repeat polymorphism with blood pressure phenotypes and its relevance to future cardiovascular mortality risk: an observation based on arsenic-exposed individuals . Atherosclerosis .2011

27. 2010 Wu MM,Chiou HY,Chen CL,Wang YH,Hsieh YC,Lien LM, Lee TC, Chen CJ. GT-repeat polymorphism in the heme oxygenase-1 gene promoter is associated with cardiovascular mortality risk in an arsenic-exposed population in northeastern Taiwan . Toxicology and Applied Pharmacology .2010 ;(248):226-233

28. 2010 Wu MM,Chiou HY,Lee TC,Chen CL,Hsu LI,Wang YH, Huang WL, Hsieh YC, Yang TY, Lee CY, Yip PK, Wang CH, Hsueh YM, Chen CJ. GT-repeat polymorphism in the heme oxygenase-1 gene promoter and the risk of carotid atherosclerosis related to arsenic exposure . Journal of Biomedical Science .2010 ;(17):70

29. 2010 Wu MM,Hsieh YC,Lien LM,Chen WH,Bai CH,Chiu HC, Chen HH, Chung WT, Lee YC, Hsu CY, Lin HW, Chiou HY. Association of estrogen receptor {alpha} genotypes/ haplotypes with carotid intima-media thickness in Taiwanese women . Angiology .2010 ;(61):275-282

30. 2007 Wang YH,Wu MM,Hong CT,Lien LM,Hsieh YC,Tseng HP, Chang SF, Su CL, Chiou HY, Chen CJ.. Effects of arsenic exposure and genetic polymorphisms of p53, glutathione S-transferase M1, T1, and P1 on the risk of carotid atherosclerosis in Taiwan. . Atherosclerosis. .2007

31. 2007 Wang CH,Hsiao CK,Chen CL,Hsu LI,Chiou HY,Chen SY, Hsueh YM, Wu MM, Chen CJ. A review of the epidemiologic literature on the role of environmental arsenic exposure and cardiovascular diseases. . Toxicol Appl Pharmacol. .2007

32. 2007 Chen CJ,Wang SL,Chiou JM,Tseng CH,Chiou HY,Hseuh YM, Chen SY, Wu MM, Lai MS.. Arsenic and diabetes and hypertension in human populations: A review. . Toxicol Appl Pharmacol. .2007

33. 2006 Tseng HP,Wang YH,Wu MM,The HW,Chiou HY,Chen CJ. Association between chronic exposure to arsenic and slow nerve conduction velocity among adolescents in Taiwan. . J Health Popul Nutr. .2006 ;(24):182-189

34. 2006 Wu MM,Chiuo HY,Hsueh YM,Hong CT,Su CL,Chang SF, Huang WL, Wang HT, Wang YH, Hsieh YC, Ch. Effect of plasma homocysteine level and urinary monomethylarsonic acid on the risk of arsenic-associated carotid atherosclerosis. . Toxicol Appl Pharmacol. .2006 ;(216):168-175

35. 2005 Chen CJ,Hsu LI,Wang CH,Shih WL,Hsu YH,Tseng MP, Lin YC, Chou WL, Chen CY, Lee CY, Wang L. Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan. . Toxicol Appl Pharmacol. .2005 ;(206):198-206

36. 2004 Chen CL,Hsu LI,Chiou HY,Hsueh YM,Chen SY,Wu MM, Chen CJ; Blackfoot Disease Study Group.. Ingested arsenic, cigarette smoking, and lung cancer risk: a follow-up study in arseniasis-endemic areas in Taiwan. . JAMA. .2004 ;(294):2984-2990

37. 2003 Wu MM,Chiou HY,Ho IC,Chen CJ,Lee TC. Gene expression of inflammatory molecules in circulating lymphocytes from arsenic-exposed human subjects. . Environ Health Perspect. .2003 ;(111):1429-1438

38. 2002 Wang CH,Jeng JS,Yip PK,Chen CL,Hsu LI,Hsueh YM, Chiou HY, Wu MM, Chen CJ.. Biological gradient between long-term arsenic exposure and carotid atherosclerosis. . Circulation. .2002 ;(105):1804-1809

39. 2001 Wu MM,Chiou HY,Wang TW,Hsueh YM,Wang IH,Chen CJ, Lee TC. Association of blood arsenic levels with increased reactive oxidants and decreased antioxidant capacity in a human population of northeastern Taiwan. . Environ Health Perspect. .2001 ;(109):1011-1017

40. 2000 Morales KH,Ryan L,Kuo TL,Wu MM,Chen CJ. Risk of internal cancers from arsenic in drinking water. . Environ Health Perspect. .2000 ;(108):655-661

研究計畫

計畫名稱
107 砷皮膚癌之分子流行病學研究:探討遺傳易感受因子單核?酸多型性與基因表現對於砷致癌風險的影響
補助單位
科技部

計畫名稱
95 雌激素相關基因異型性與心血管疾病之研究
補助單位
行政院國家科學委員會

計畫名稱
94 探討砷井水之作用標的與發炎因子對於砷誘發粥狀動脈硬化疾病之族群研究II
補助單位
行政院國家科學委員會

計畫名稱
93 探討砷井水之作用標的與發炎因子對於砷誘發周狀動脈硬化疾病之族群研究
補助單位
行政院國家科學委員會

計畫名稱
92 探討砷井水之作用標的與發炎因子對於砷誘發周狀動脈硬化疾病之族群研究
補助單位
行政院國家科學委員會