莊校奇(Chuang, Hsiao-Chi) 教授

Email
chuanghc@tmu.edu.tw
現   職
呼吸治療學系 教授

學經歷

學 歷

畢業學校與學位[修業時間]
Cardiff UniversityBiosciences 博士
2008/10~2011/11
台灣大學職業醫學與工業衛生所 碩士
2003/09~2005/06
中國醫藥大學職業安全與衛生 學士
1999/09~2003/06

本校學術經歷

任職單位與職稱[起迄時間]
呼吸治療學系教授
2020/08/01~
呼吸治療學系副教授
2016/08/01~2020/07/31
呼吸治療學系助理教授
2015/02/01~2016/07/31
呼吸治療學系助理教授
2013/02/01~2015/01/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
公共衛生學系副教授
2018/11/01 ~
內科學科助理教授
2016/08/01 ~

其它經歷

任職單位與職稱[起迄時間]
雙和醫院醫學研究員
2012/08/01~2015/01/31
宜蘭聖母醫事管理專科學校兼任助理教授
2012/02/01~2012/06/30
臺灣大學博士後研究員
2012/02~2012/07

專長與研究領域

學門領域
胸腔內科
Chest
呼吸毒理
空氣污染學
職業醫學
公共衛生及環境醫學
學術專長
環境衛生
環境衛生
環境職業醫學
環境職業醫學
環境毒理
環境毒理
Airway diseases
Airway diseases
慢性阻塞性肺疾
慢性阻塞性肺疾

論文著作

清冊下載


1. 2021 Niu X.,Wang Y.,Ho. SS.,Chuang H-C.,Sun J.,Qu L., Wang G., Ho KF.*. Characterization of organic aerosols in PM1 and their cytotoxicity in an urban roadside area in Hong Kong . Chemosphere .2021 ;(263):128239.

2. 2021 Chang C-J.,Lin, C-F.,Lee C-H., ,Chuang H-C.,Shih F-J.,Wan S-W., Tai C., Chen C-L.*. Overcoming interferon (IFN)-γ resistance ameliorates transforming growth factor (TGF)-β-mediated lung fibroblast-to-myofibroblast transition and bleomycin-induced pulmonary fibrosis . Biochemical Pharmacology .2021 ;(183):114356

3. 2021 Niu X.,Jones T.,BéruBé K. ,Chuang H-C.,Sun J.,Ho K-F.*. The oxidative capacity of indoor source combustion derived particulate matter and resulting respiratory toxicity . Science of the Total Environment .2021 ;(767):144391

4. 2021 Li Z.,Ho K-F. ,Chuang H-C.,Yim S.H.L.*. Development and intercity transferability of land-use regression models for predicting ambient PM10, PM2.5, NO2 and O3 concentrations in northern Taiwan . Atmospheric Chemistry and Physics .2021 ;(21):5063-5078

5. 2021 Lo K.#,Chiang L-L.#,Hsu S-M.,Tsai C-Y., Wu D.,Chou C-J., Chuang H-C.*, Liu W-T.*. Association of Short-term Exposure to Air Pollution with Depression in Patients with Sleep-related Breathing Disorders. . Science of the Total Environment .2021 ;(786):147291

6. 2021 Chang L-T.#,Lee Y-L.#,Yuan T-H.,Chang J-H.,Chang T-Y. ,Lee C-H., Ho K-F., Chuang H-C.*. Hepatotoxicity caused by repeated and subchronic pulmonary exposure to low-level vinyl chloride in mice . Atmosphere .2021 ;(12):596

7. 2021 Nguyen TT.,Ho K-F.,Niu X.,Sun J.,Shen Z.,Wu F., Cao J., Hoang BD, Tran PCT, Hsiao T-C., Liu W-T.*, Chuang H-C.*. Loss of E-cadherin due to road dust PM2.5 activates the EGFR in human pharyngeal epithelia cells . Environmental Science and Pollution Research .2021

8. 2021 Nguyen T.T.,Lee Y-L.,Lin S-Y.,Wu C-D.,Hoang B.D.,Tran P.C.T., Tsai C-Y., Lo C-C., Lo K., Ho K-F., Liu W-T.*, Chuang H-C.*. Associations of ambient air pollution with overnight changes in body composition and sleep-related parameters. . Science of the Total Environment .2021 ;(791):148265

9. 2021 Jheng Y-T.#,Putri D.U.#,Chuang H-C.,Lee K-Y.,Chou H-C.,Wang S-Y., Han C-L.*. Prolonged exposure to traffic-related particulate matter and gaseous pollutants implicate distinct molecular mechanisms of lung injury in rats . Particle and Fibre Toxicology .2021 ;(18):24

10. 2021 Nguyen T.T.,Ho S-C.,Lu Y-H.,Chen T-T.,Lee K-Y.,Chen K-Y., Wu C-D., Chung K-F., Kuo H-P., Huynh N.X.T., Hoang B.D., Tran P.C.T., Wu S-M., Kou H-Y., Lee Y-L., Chuang H-C.*. Higher alveolar deposition of particulate matter in emphysematous lobes of COPD . ERJ Open Research .2021 ;(7):00324-2021

11. 2021 Bandowe B.A.M.,Lui K.H.,Jones T.,BéruBé K.,Adams R.,Niu X., Wei C., Cao J-J., Lee S.C., Chuang H-C., Ho K-F.*. The chemical composition and toxicological effects of fine particulate matter (PM2.5) emitted from different cooking styles . Environmental Pollution .2021 ;(288):117754

12. 2021 Lee S-H.,Chen Y-H.,Chien C-C.,Yan Y-H.,Chen H-C.,Chuang H-C., Hsieh H-I., Cho K-H., Kou L-W., Chou C.C-K., Chiu M-J., Tee B.L., Chen T-F.*, Cheng T-J.*. Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model . Plos One .2021 ;(16):e0254587

13. 2021 Bai K-J.#,Nguyen T.T.#,Hsiao T-C.,Chen T-L.,Ho S-C.,Tsai T-Y., Chen J-K., Lee C-N., Lee K-Y., Chang C-C., Chen T-T., Feng P-H., Chen K-Y., Su C-L., Huynh N.X.T., Hoang B.D., Tran P.C.T., Lee Y-L.*, Chuang H-C.*. Associations between lung‐deposited dose of particulate matter and culture-positive pulmonary tuberculosis pleurisy . Environmental Science and Pollution Research .2021

14. 2021 Sun J.,Yu J.,Shen Z.*,Niu X.,Wang D.,Wang X., Xu H., Chuang H-C., Cao J., Ho K-F.. Oxidative Stress–Inducing Effects of Various Urban PM2.5 Road Dust on Human Lung Epithelial Cells among 10 Chinese Megacities . Ecotoxicology and Environmental Safety .2021 ;(18):112680

15. 2021 Nguyen TT.,Hoang BD.,Tran PCT.,Huynh NXT.,Chuang H-C.*. Air Pollution and Respiratory Permeability in Obstructive Sleep Apnea - A Review . Aerosol and Air Quality Research .2021

16. 2021 Lai C-H.,,Ho S-C.,Pan C-H.,Chen W-L.,Wang C-C.,Liang C-W., Chien C-Y., Riediker M., Chuang K-J., Chuang H-C.* . Chronic exposure to metal fume PM2.5 on inflammation and stress hormone cortisol in shipyard workers: A repeat measurement study . Ecotoxicology and Environmental Safety .2021 ;(215):112144

17. 2021 Chen X-Y., ,Feng P-H., ,Han C-L., ,Jheng Y-T., ,Wu C-D., ,Chou H-C., Chen Y-Y., Wu S-M., Lee K-Y., Kuo H-P., Chung KF., Hsiao T-C., Chen K-Y., Ho S-C., Chang T-Y., Chuang H-C.*. Alveolar epithelial inter-alpha-trypsin inhibitor heavy chain 4 deficiency associated with senescence-regulated apoptosis by air pollution . Environmental Pollution .2021 ;(278):116863

18. 2021 Chang T-Y.*,Tsai C-C.,Wu C-F.,Chang L-T.,Chuang K-J. ,Chuang H-C., Young L-H.. Development of land-use regression models to estimate particle mass and number concentrations in Taichung, Taiwan . Atmospheric Environment .2021 ;(252):118303

19. 2021 Chen X-C.,Chuang H-C.,Ward T.J.,Sarkar C.,Webster C.,Cao J., Hsiao T-C., Ho K-F.*. Toxicological effects of personal exposure to fine particles in adult residents of Hong Kong . Environmental Pollution .2021 ;(275):116633

20. 2020 Hsiao T-C.*, Chuang H-C.,Lin J-C.,Cheng T-J.,Chou L-T.. Effect of particle morphology on performance of an electrostatic air-liquid interface cell exposure system for nanotoxicology studies . Nanotoxicology .2020

21. 2020 Chuang H-C.,Chen H-C.,Chai P-J.,Liao H-T.,Wu C-F.,Chen C-L., Jhan M-K., Hsieh H-I., Wu K-Y., Chen T-F., Cheng T-J.*. Neuropathology changed by 3- and 6-months low-level PM2.5 inhalation exposure in spontaneously hypertensive rats . Particle and Fibre Toxicology .2020

22. 2020 Bai K-J.,Ho S-C.,Tsai C-Y.,Chen J-K.,Lee C-N.,Lee K-Y., Chang C-C., Chen T-T., Feng P-H., Chen K-Y., Su C-L., Chuang H-C.*. Exposure to PM2.5 is associated with malignant pleural effusion in lung cancer patients . Ecotoxicology and Environmental Safety .2020

23. 2020 Wang B.*,Lau Y-S.,Huang Y.,Organ B.,Chuang H-C.,Lee S-C., Ho K-F.*. Chemical and toxicological characterization of particulate emissions from diesel vehicles . Journal of Hazardous Materials .2020

24. 2020 Hsiao T-C.#,Chuang H-C.#,Griffith S.M.,Chen S-J.,Lin W-Y.,Young L-H.*. COVID-19: An aerosol’s point of view from expiration to transmission to viral-mechanism . Aerosol and Air Quality Research .2020 ;(20):905-910

25. 2020 Chuang H-C.,Yang Y-T.,Chen H-C.,,Hwang Y-H.,,Wu K-Y.,Chen T-F., Chen C-L., Jhan M-K., Cheng T-J.*. Acute effects of pulmonary exposure to zinc oxide nanoparticles on brain in vivo . Aerosol and Air Quality Research .2020 ;(20):1651-1664

26. 2020 Niu, X,Chuang H-C.,Wang X.,,Ho SSH.,Li L.,Qu L., Chow JC., Watson JG., Sun J., Lee S., Cao J., Ho KF.*. Cytotoxicity of PM2.5 vehicular emissions in the Shing Mun Tunnel, Hong Kong . Environmental Pollution .2020 ;(263):114386

27. 2020 Hsiao T-C.,,Chang J-S.,Wang J-Y.,Wu D.,Chuang K-J.,Chen J-K., Cheng T-J., Chuang H-C.*. Serum Neurofilament Light Polypeptide is a Biomarker for Inflammation in Cerebrospinal Fluid Caused by Fine Particulate Matter . Aerosol and Air Quality Research .2020 ;(20):1665-1674

28. 2020 Chen X.,Chuang H-C.,Ward T.J.,Tian L., Cao J-J.,Ho S., Lau N-C., Hsiao T-C., Yim S., Ho KF.* . Indoor, outdoor, and personal exposure to PM2.5 and their bioreactivity among healthy residents of Hong Kong . Environmental Research .2020 ;(10):109780

29. 2020 Chuang H-C.*,Shie R-H.,Lee C-H.,Chio C-P.,Yuan T-Z.,Lee J-H., Chan C-C.*. Associations of soluble metals and lung and liver toxicity in mice induced by fine particulate matter originating from a petrochemical complex . Environmental Science and Pollution Research .2020

30. 2020 Lai C-H.*,Chou C-C.,Chuang H-C.,Lin G-J.,Pan C-H.,Chen W-L.. Receptor for advanced glycation end products in relation to exposure to metal fumes and polycyclic aromatic hydrocarbon in shipyard welders . Ecotoxicology and Environmental Safety .2020

31. 2020 Wu S-M.,Feng P-H.,Chuang H-C.,Ho S-C.,Chung K.F.,Chen K-Y., Wu G-S., Chen T-T., Tseng C-H., Liu W-T., Lee K-Y.*. Impaired lnc-IL7R modulatory mechanism of Toll-like receptors is associated with an exacerbator phenotype of chronic obstructive pulmonary disease . FASEB J .2020

32. 2020 Nguyen T.,Cheng P-C.,Chi K-H.,Hsiao T-C.,Jones T.,BéruBé K., Ho K-F., Chuang H-C.*. Particulate Matter and SARS-CoV-2: a possible model of COVID-19 Transmission . Science of the Total Environment .2020

33. 2020 Chen X-Y.,Chen Y-Y.,Lin W.,Chien C-W.,Chen C-H.,,Wen Y-C., Hsiao T-C., Chuang H-C.*. Effects of human umbilical cord-derived mesenchymal stem cells on the acute cigarette smoke-induced pulmonary inflammation model . Frontiers in Physiology-Respiratory Physiology .2020 ;(11):962

34. 2020 Chuang H-C.,Tsai S-W.,Shie R-H.,Lu Y-C.,Song S-R.,Huang S-H., Peng H-Y., Yang H-Y.*. A novel lung alveolar cell model for exploring volatile biomarkers of particle-induced lung injury . Scientific Reports .2020 ;(10):15700

35. 2020 Chuang H-C.*#,Chen Y-Y.,Hsiao T-C.,Chou H-C.,Kuo H-P.,Feng P-H., Ho S-C., Chen J-K., Chuang K-J., Lee K-Y.*#. Alteration in angiotensin-converting enzyme 2 by PM1 during the development of emphysema in rats . ERJ Open Research .2020 ;(6):00174-2020

36. 2020 Chen H-L.,Li C-P.,Tang C-S.,Lung S-C.,Chuang H-C.,,Chou D-W., Chang L-T.*. Risk Assessment for People Exposed to PM2.5 and Constituents at Different Residential Heights in an Urban Area of Taiwan . Atmosphere .2020 ;(11):1145

37. 2019 Chang L-T.,Hong G-B.,Weng S-P.,Chuang H-C.,Chang T-Y.,Liu C-W., Chuang W-Y., Chuang K-J.*. Indoor ozone levels, houseplants and peak expiratory flow rates among healthy adults in Taipei, Taiwan. . Environment International .2019 ;(245):675-683

38. 2019 Lee P-L.,Lee K-Y.,Cheng T-M.,Chuang H-C.,Wu S-M.,Feng P-H., Liu W-T., Chen K-Y., Ho S-C.*. Relationships of Haptoglobin Phenotypes with Systemic Inflammation and the Severity of Chronic Obstructive Pulmonary Disease . Scientific Reports .2019 ;(9):189

39. 2019 Chuang H-C.*. Air Pollution and Respiratory System . Frontline Pediatrics .2019 ;(27):81-82

40. 2019 Cheng N-Y.,Chuang H-C.,Shie R-H.,Liao W-H.,Hwang Y-H.*. Pilot Studies of VOC Exposure Profiles during Surgical Operations . Annals of Work Exposures and Health .2019 ;(63):173-183

41. 2019 Bai K-J.,Chuang K-J.,Chen J-K.,Tsai C-Y.,Yang Y-L.,Chang C-C., Chen T-T., Lee C-N., Feng P-H., Chen K-Y., Lee K-Y., Su C-L., Ho S-H., Wu S-M., Chuang H-C.*. Alterations by air pollution in inflammation and metals in pleural effusion of pneumonia patients . International Journal of Environmental Research and Public Health .2019 ;(16):705

42. 2019 Hsu Y-H.,Chuang H-C.,Lee Y-H.,Lin Y-F.,Chen Y-J.,Hsiao T-C., Wu M-Y., Chiu H-W.*. Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo . Free Radical Biology and Medicine .2019 ;(135):235-244

43. 2019 Ho S-C.,Chuang K-J.,Lee K-Y.,Chen J-K.,Wu S-M.,Chen T-T., Lee C-N., Chang C-C., Feng P-H., Chen K-Y., Su C-L., Tsai C-Y., Chuang H-C.*. Chronic obstructive pulmonary disease patients have a higher risk of occurrence of pneumonia by air pollution . Science of the Total Environment .2019 ;(667):524-529

44. 2019 Hsu Y-H.,Chuang H-C.,Lee Y-H.,Lin Y-F.,Chiu Y-J.,Wang Y-L., Wu M-S*, Chiu H-W.*. Induction of fibrosis and autophagy in kidney cells by vinyl chloride . Cells .2019 ;(8):601

45. 2019 Pangaribuan M.,Chuang K-J.*,Chuang H-C.. Association between exposures to air pollution and biomarkers of cardiovascular disease in northern Taiwan . Atmospheric Pollution Research .2019 ;(10):1250-1259

46. 2019 Tang C-S.,Wu T-Y.,Chuang K-J.,Chang T-Y.,Chuang H-C.,Lung S-C., Chang L-T.*. Impacts of in-cabin exposure to multi-sized particulate matters and carbon monoxide on changes in heart rate variability for healthy public transit commuters . Atmosphere .2019 ;(10):409-409

47. 2019 Niu X.,Ho K-F.*,Chuang H-C.,Sun J.,Huang Y.,Hu T., Xu H., Duan J., Lui K., Cao J.*. Comparison of cytotoxicity induced by PM2.5-bound polycyclic aromatic compounds from different environments in Xi'an . Atmospheric Environment .2019 ;(216):116929

48. 2019 Bai K-J.,Chuang K-J.,Chen C-L.,Jhan M-K.,Hsiao T-C.,Cheng T-J., Chang L-T., Chang T-Y., Chuang H-C.*. Microglial activation and inflammation caused by traffic-related particulate matter . Chemico-Biological Interactions .2019 ;(311):108762

49. 2019 Tang C-S.,Chuang K-J.,Chang T-Y.,Chuang H-C.,Chen L-H.,Lung S-C., Chang L-T.*. Effects of microenvironmental exposure to micro- and nano-particulate matter, black carbon, particle-bound polycyclic aromatic hydrocarbons, and carbon monoxide on heart rate variability in a panel of healthy older subjects . International Journal of Environmental Research and Public Health .2019 ;(16):4672

50. 2019 Chuang H-C.#,Sun J.#,Ni H.,Tian J.,Lui K.H.,Han Y., Cao J., Huang R-J., Shen Z., Ho K-F.* . Characterization of Chemical Components and Bioreactivity of Fine Particulate Matter (PM2.5) during Burning of Crop Residues in China. . Environmental Pollution .2019 ;(245):226-234

51. 2018 Shih C-H.,Chen J-K.,Kuo L-W.,Cho K-H.,Hsiao T-C.,Lin Z-W., Lin Y-S., Kang J-H., Lo Y-C., Chuang K-J., Cheng T-J., Chuang H-C.* . Chronic pulmonary exposure to traffic-related fine particulate matter causes brain impairment in adult rats. . Particle and Fibre Toxicology .2018 ;(15):44

52. 2018 Ho K-F.,Wu K-C.,Niu X.,Wu Y.,Zhu C-S.,Wu F., Cao J-J., Shen Z-X., Hsiao T-C., Chuang K-J., Chuang H-C.*. Contributions of local pollution emissions to particle bioreactivity in downwind cities in China during Asian dust periods. . Environmental Pollution .2018

53. 2018 Feng P-H.,Yu C-T.,Chen K-Y.,Luo C-S.,Wu S-M.,Liu C-Y., Kuo L-W., Chan Y-F., Chen T-T., Chang C-C., Lee C-N., Chuang H-C., Lin C-F., Han C-L., Lee W-H., Lee K-Y.*. S100A9+ MDSC and TAM-mediated EGFR-TKI Resistance in Lung Adenocarcinoma: The Role of RELB. . Oncotarget .2018 ;(9):7631-7643

54. 2018 Liu J-Y.,Hsiao T-C.,Lee K-Y.,Chuang H-C.,Cheng T-J.,Chuang K-J.*. Association of ultrafine particles with cardiopulmonary health among adult subjects in the urban areas of northern Taiwan. . Science of the Total Environment .2018 ;(627):211-215

55. 2018 Chuang H-C.,Shie R-H.,Chio C-P.,Yuan T-H.,Lee J-H.,Chan C-C.. Cluster analysis of fine particulate matter (PM2.5) emissions and its bioreactivity in the vicinity of a petrochemical complex . Environmental Pollution .2018 ;(236):591-597

56. 2018 Chuang H-C.*,Wu D.,Kang J-H.. Particulate air pollution and neurological diseases: the role of tauopathies . Environmental Disease .2018 ;(3):4-7

57. 2018 Feng P-H.,Chen K-Y.,Huang Y-C.,Lou C-S.,Wu S-M.,Chen T-T., Lee C-N., Yeh C-T., Chuang H-C., Han C-L., Lin C-F., Lee W-H., Kuo C-H.,* Lee K-Y.* . Bevacizumab Reduces S100A9 + MDSC Linked to Intracranial Control in Patients with EGFR Mutant Lung Adenocarcinoma. . Journal of Thoracic Oncology .2018 ;(13):958-967

58. 2018 Yang W-T.,Wang V-S.,Chang L-T.,Chuang K-J.,Chuang H-C.,Liu C-S., Bao B-Y., Chang T-Y.*. Road traffic noise, air pollutants and the prevalence of cardiovascular disease in Taichung, Taiwan. . International Journal of Environmental Research and Public Health .2018 ;(15):1707

59. 2018 Bai K-J.,Chuang K-J.,Wu S-M.,Chang L-T.,Chang T-Y.,Ho K-F., Chuang H-C.*. Effects of diesel exhaust particles on the expression of tau and autophagy proteins in human neuroblastoma cells. . Environmental Toxicology and Pharmacology .2018 ;(62):54-59

60. 2018 Yang T-T.#,Chuang K-J.#,Chang N-Y.,Pan C-H.,Liao W-H.,Liao C-C., Tsuang Y-H., Wen H-Y., Hsiao T-C.*#, Chuang H-C.*# . Exposure assessment of particulate and gaseous pollutants emitted during surgery in operating rooms of different specialties . Air Quality, Atmosphere & Health .2018 ;(11):937-947

61. 2018 Shen Y-L.,Liu W-T.,Lee K-Y.,Chuang H-C.,Chen H-W.,Chuang K-J.*. Association of PM2.5 with sleep-disordered breathing from a population-based study in Northern Taiwan urban areas . Environmental Pollution .2018 ;(233):109-113

62. 2017 Ba K-J.#,Chuang K-J.#,Chen J-K.,Hua H-E.,Shen Y-L.,Liao W-N., Lee C-H., Chen K-Y., Lee K-Y., Hsiao T-C., Pan C-H., H, K-F., Chuang H-C.*. Investigation into the pulmonary inflammopathology of exposure to nickel oxide nanoparticles in mice . Nanomedicine: Nanotechnology, Biology, and Medicine .2017

63. 2017 Chuang H-C.,Lin Y-J.,Chou CC.,Hwang J-S.,Chen C-C.,Yan Y-H., Hsieh H-I., Chuang K-J., Cheng T-J.*. Alterations in cardiovascular function by particulate matter in rats using a crossover design . Environmental Pollution .2017 ;(231):812-820

64. 2017 Lee K-Y.,Feng P-H.,Chuang H-C.,Wu S-M.,Liu W-T.,Chen K-Y., Liu C-Y., Ho S-C.*. Trace elements in pleural effusion correlates with smokers with lung cancer . Biological Trace Element Research .2017

65. 2017 Chuang H-C.,Hsiao T-C.,Lee C-H.,Lin C-T.,Chuang K-J.,Feng P-H., Cheng T-J.*. Effects of physical characteristics of carbon black on metabolic regulation in mice . Environmental Pollution .2017 ;(232):494-504

66. 2017 Chuang H-C.*,Su T-Y.,Chuang K-J.,Hsiao T-C.,Lin H-L.,Hsu Y-T., Pan C-H., Lee K-Y., Ho S-C., Lai C-H.*. Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders . Environmental Pollution .2017 ;(232):523-532

67. 2017 Yang T-T.*,Ho S-C.,Chuang L-T.,Chuang H-C.,Li Y-T.,Wu J-J.. Characterization of Particulate-Phase Polycyclic Aromatic Hydrocarbons Emitted from Incense Burning and their Bioreactivity in RAW264.7 Macrophage . Environmental Pollution .2017 ;(220):1190-1198

68. 2017 Hsiao T-C.*,Chuang H-C.,Chen C-W.,Cheng T-J.,Chang Chien Y-C.. Development and collection efficiency of an electrostatic precipitator for in-vitro toxicity studies of nano- and submicron-sized aerosols . Journal of the Taiwan Institute of Chemical Engineers .2017 ;(72):1-9

69. 2017 Wu S-M.,Lin S-L.,Lee K-Y.,Chuang H-C.,Feng P-H.,Cheng W-L., Liao C-J., Chi H-C., Lin Y-H., Tsai C-Y., Chen W-J., Yeh C-T., Lin K-H.*. Hepatoma cell functions modulated by NEK2 are associated with liver cancer progression . International Journal of Cancer .2017 ;(140):1581-1596

70. 2017 Lin C-F.*,Lin C-M.,Lee K-Y.,Wu S-Y.,Feng P-H.,Chen K-Y., Chuang H-C., Chen C-L., Wang Y-C., Tseng P-C., Tsai T-T.. Escape from IFN-γ-dependent immunosurveillance in tumorigenesis . Journal of Biomedical Science .2017 ;(24):10

71. 2017 Ho S-C.,Wu S-M.,Feng P-H.,Liu W-T.,Chen K-Y.,Chuang H-C., Chan Y-F., Kuo L-W., Lee K-Y.*. Noncanonical NF-κB mediates the suppressive effect of neutrophil elastase on IL-8/CXCL8 by inducing NKRF in human airway smooth muscle . Scientific Reports .2017 ;(7):44930

72. 2017 Chen T-T.,Wu S-M.,Ho S-C.,Chuang H-C.,Liu C-Y.,Chan Y-F., Kuo L-W., Feng P-H., Liu W-T., Chen K-Y., Hsiao T-C., Juang J-N., Lee K-Y.*. SUV39H1 reduction is implicated in abnormal inflammation in COPD . Scientific Reports .2017 ;(7):46667

73. 2017 Chuang H-C.*,Chuang K-J.,Chen J-K.,Hua H-E.,Shen Y-L.,Liao W-N., Lee C-H., Pan C-H., Chen K-Y., Lee K-Y., Hsiao T-C., Cheng T-J.. Pulmonary pathobiology induced by zinc oxide nanoparticles in mice: a 24-hour and 28-day follow-up study . Toxicology and Applied Pharmacology .2017 ;(327):13-22

74. 2017 Lee K-Y.#,Chen T-T.#,Chiang L-L.,Chuang H-C.,Feng P-H.,Liu W-T., Chen K-Y., Ho S-C.*. Proteasome activity related with the daily physical activity of COPD patients . International Journal of Chronic Obstructive Pulmonary Disease .2017 ;(12):1519-1525

75. 2017 Chuang H-C.,Ho K-F.,Lin L-Y.,Chang T-Y.,Hong G-B.,Ma C-M., Liu I-J., Chuang K-J.*. Long-term indoor air conditioner filtration and cardiovascular health: A randomized crossover intervention study . Environment International .2017 ;(106):91-96

76. 2017 Bai K-J.,Chuang K-J.,Ma C-M.,Chang T-Y.,Chuang H-C.*. Human lung adenocarcinoma cells with an EGFR mutation are sensitive to non-autophagic cell death induced by zinc oxide and aluminium-doped zinc oxide nanoparticles . The Journal of Toxicological Sciences .2017 ;(42):437-444

77. 2016 Ho K-F.*,Ho S.,Huang R-J.,Chuang H-C.*,Cao J-J.,Han Y-M., Lui K-H., Ning Z., Chuang K-J., Cheng T-J., Lee S-C., Hu D., Wang B., Zhang R-J.. Chemical composition and bioreactivity of PM2.5 during 2013 haze events in China . Atmospheric Environment .2016 ;(126):162-170

78. 2016 Chen K-Y.#,Chuang K-J.#,Liu H-C.,Lee K-Y.,Feng P-H.,Su C-L., Lin C-L., Lee C-L., Chuang H-C.*. Particulate matter is associated with sputum culture conversion in patients with culture-positive tuberculosis . Therapeutics and Clinical Risk Management .2016 ;(12):41-46

79. 2016 Lui, K-H.,Bandowe, B.,Ho, S.,Chuang, H-C.*,Cao, J-J.,Chuang, K-J., Lee, S-C., Hu, D., Ho, K-F.*. Characterization of chemical components and bioreactivity of fine particulate matter (PM2.5) during incense burning . Environmental Pollution .2016 ;(213):524-532

80. 2016 Chuang H-C.,Hsiao T-C.*,Wang S-H.,Tsay S-C.,Lin N-H.. Characterization of particulate matter profiling and alveolar deposition from biomass burning in Northern Thailand: The 7-SEAS study . Aerosol and Air Quality Research .2016

81. 2016 Lin S-C.,Hunag J-J.,Wang J-Y.,Chuang H-C.,Chiang B-L.,Ye Y-L.*. Upregulated Thymic Stromal Lymphopoietin Receptor Expression in Children with Asthma. . European Journal of Clinical Investigation .2016 ;(46):511-519

82. 2016 Chuang K-J.#,,Lee K-Y.#,Pan C-H.,Lai C-H.,Lin L-Y.,Ho S-C., Ho K-F., Chuang H-C.*. Effects of zinc oxide nanoparticles on human coronary artery endothelial cells. . Food and Chemical Toxicology .2016 ;(93):138-144

83. 2016 Chen K-Y.,Feng P-H.,Chang C-C.,Chen T-T.,Chuang H-C.,Lee C-N., Su C-L., Lin L-Y., Lee K-Y.*. Novel biomarker analysis of pleural effusion enhances differentiation of tuberculous from malignant pleural effusion . International Journal of General Medicine .2016 ;(9):183-189

84. 2016 Lee K-Y.#,Chiang L-L.#,Ho S-C.,Liu W-T.,Chen T-T.,Feng P-H., Su C-L., Chuang K-J., Chang C-C., Chuang H-C.*. Associations of autophagy with the lung diffusion capacity and oxygen saturation in severe COPD: Effects of particulate air pollution . International Journal of Chronic Obstructive Pulmonary Disease .2016 ;(11):1569-1578

85. 2016 Ho S-C.,Wang J-Y.,Kuo H-P.,Huang C-D.,Lee K-Y.,Chuang H-C., Feng P-H., Chen T-T., Hsu M-F.*. Mid-Arm and Calf Circumferences Are Stronger Mortality Predictors than Body Mass Index for Patients with Chronic Obstructive Pulmonary Disease . International Journal of Chronic Obstructive Pulmonary Disease .2016 ;(11):2075-2080

86. 2016 Lai C-Y.,Lai C-H.,Chuang H-C.*,Pan C-H.,Yen C-C.,Lin W-Y., Chen J-K., Lin L-Y., Chuang K-J.*. Physicochemistry and cardiovascular toxicity of metal fume PM2.5: a study of human coronary artery endothelial cells and welding workers . Scientific Reports .2016 ;(6):33515

87. 2016 Lai C-H.#,Lee C-N.#,Bai K-J.,Yang Y-L.,Chuang K-J.,Wu S-M., Chuang H-C.*. Protein oxidation and degradation caused by particulate matter . Scientific Reports .2016 ;(6):33727

88. 2016 Han B-C.,Liu I-J.,Chuang H-C.,Pan C-H.,Chuang K-J.*. Effect of welding fume on heart rate variability among workers with respirators in a shipyard . Scientific Reports .2016 ;(6):34158

89. 2016 Ho K-F.#,Chang C-C.#,Tian L-W.,Chan C-S.,Bandowe A.,Lui K-H., Lee K-Y., Chuang K-J., Liu C-Y., Ning Z., Chuang H-C.*. Effects of polycyclic aromatic compounds in fine particulate matter generated from household coal combustion on response to EGFR mutations in vitro . Environmental Pollution .2016 ;(218):1262-1269

90. 2016 Tsay, S-C.*,Maring, H.,Lin, N-H.*,Buntoung, S.,Chantara, S.,Chuang, H-C., Gabriel, P., Goodloe, C., Holben, B., Hsiao, T.C., Hsu, N., Janjai, S., Lau, W., Lee,. Satellite-surface perspectives of air quality and aerosol-cloud effects on the environment: An overview of 7-SEAS/BASELInE . Aerosol and Air Quality Research .2016 ;(16):2851-2602

91. 2016 Liu W-T.,Lee K-Y.,Lee H-C.,Chuang H-C.,Wu D.,Juang J-N., Chuang K-J.*. The association of annual air pollution exposure with blood pressure among patients with sleep-disordered breathing . Science of the Total Environment .2016 ;(543):61-66

92. 2015 Chuang K-J.#,Pan C-H.#,Su C-L.,Lai C-H.,Lin W-Y.,Ma C-M., Ho S-C., Bien M-Y., Chuang H-C.*. Urinary neutrophil gelatinase-associated lipocalin is associated with heavy metal exposure in welding workers . Scientific Reports .2015 ;(5):18048

93. 2015 Yang T-H.,Masumi S.,Weng S-P.,Chen H-W.,Chuang H-C.,Chuang K-J.. Personal exposure to particulate matter and inflammation among patients with periodontal Disease. . Science of the Total Environment .2015 ;(502):585-589

94. 2015 Ho K-F.,Ho S.,Huang R-J.,Liu S-X.,Cao J-J.,Zhang T., Chuang H-C., Chan C-S., Hu D., Tian L-W.. Characteristics of water-soluble organic nitrogen in fine particulate matter in the continental area of China . Atmospheric Environment .2015 ;(106):252-261

95. 2015 Chuang H-C.,Chen L-C.,Lei Y-C.,Wu K-Y.,Feng P-H.,Cheng, T-J.. Surface area as a dose metric for carbon black nanoparticles: a study of oxidative stress, DNA single-strand breakage and inflammation in rats. . Atmospheric Environment .2015 ;(106):329-334

96. 2015 Lee K-Y.,Cao J-J.,Lee C-H.,Hsiao T-C.,Yeh C-T.,Huynh T-T., Han Y-M., Li X-D., Chuang K-J., Tian L-W., Ho K-F.*,#, Chuang H-C.*,#. Inhibition of the WNT/β-catenin pathway by fine particulate matter in haze: Roles of metals and polycyclic aromatic hydrocarbons. . Atmospheric Environment .2015 ;(109):118-129

97. 2015 Liu W-T.,Ma C-M.,Liu I-J.,Han B-C.,Chuang H-C.,Chuang K-J.. Effects of commuting mode on air pollution exposure and cardiovascular health among young adults in Taipei, Taiwan . International Journal of Hygiene and Environmental Health .2015 ;(218):319-323

98. 2015 Lee K-Y.,Feng P-H.,Ho S-C.,Chuang K-J.,Chen T-T.,Su C-L., Liu W-T., Chuang H-C.#. Inter-alpha-trypsin inhibitor heavy chain 4: a novel biomarker for environmental exposure to particulate air pollution in patients with chronic obstructive pulmonary disease . International Journal of Chronic Obstructive Pulmonary Disease .2015 ;(10):831-841

99. 2015 Feng P-H.#,Huang Y-L.#,Chuang K-J.,Chen K-Y.,Lee K-Y.,Ho S-C., Bien M-Y., Yang Y-L., Chuang H-C.*. Dysfunction of methionine sulfoxide reductases to repair damaged proteins by nickel nanoparticles. . Chemico-Biological Interactions .2015 ;(236):82-89

100. 2015 Chang L-T.,Chuang K-J.,Yang W-T.,Wang V-S.,Chuang H-C.,Bao B-Y., Liu C-S, Chang T-Y.. Short-term exposure to noise, fine particulate matter and nitrogen oxides on ambulatory blood pressure: a repeated-measure study . Environmental Research .2015 ;(104):634-640

101. 2015 Chuang H-C.*,#,Ho K-F.#,Cao J-J.,Chuang K-J.,Ho S,Feng P-H., Tian L., Lee C-H., Han Y-M., Lee C-N., Cheng T-J.. Effects of non-protein-type amino acids of fine particulate matter on E-cadherin and inflammatory responses in mice . Toxicology Letters .2015 ;(237):174-180

102. 2015 Pan C-H.#,Chuang K-J.#,Chen J-K.,Hsiao T-C.,Lai C-H.,Jones T., BéruBé K., Hong G-B., Ho K-F., Chuang H-C.*. Characterisation of pulmonary protein profiles in response to zinc oxide nanoparticles in mice: A 24-hour and 28-day follow-up study . International Journal of Nanomedicine .2015 ;(10):4705-4706

103. 2015 Liu W-T.#,Kuo H-P.#,Liao T-H.,Chiang L-L.,Chen L-F.,Hsu M-F., Chuang H-C., Lee K-Y., Huang C-D., Ho S-C.*. Low bone mineral density in osteoporosis COPD patients related to low daily physical activity and high CAT score. . International Journal of Chronic Obstructive Pulmonary Disease .2015 ;(10):1737-1744

104. 2015 Ho S-C.*,Hsu M-F.*,Kuo H-P.,Wang J-Y.,Chen L-F.,Lee K-Y., Chuang H-C.. The relationship between anthropometric indicators and walking distance in patients with chronic obstructive pulmonary disease . International Journal of Chronic Obstructive Pulmonary Disease .2015 ;(10):1857-1862

105. 2015 Lee K-Y.,Chuang H-C.,Chen T-T.,Liu W-T.,Su C-L.,Feng P-H., Chiang L-L., Bien M-Y., Ho S-C.*. Proteoglycan 4 is a diagnostic biomarker for COPD . International Journal of Chronic Obstructive Pulmonary Disease .2015 ;(9):1999-2007

106. 2015 Chuang H-C.#,Su C-L.#,Liu H-C.,Feng P-H.,Lee K-Y.,Chuang K-J., Lee C-N., Bien M-Y*.. Cigarette smoke is a risk factor of the severity and treatment outcome in patients with cultured-positive tuberculosis . Therapeutics and Clinical Risk Management .2015 ;(11):1539-1544

107. 2015 Chuang H-C.*,Ho S-C.,Lee K-Y.,Chuang K-J.. Particulate Air Pollution and Chronic Obstructive Pulmonary Disease: The Role of Protein Oxidation. . Austin Journal of Public Health and Epidemiology .2015 ;(2):1024

108. 2014 Chuang H-C.,Juan H-T.,Chang C-N.,Yan Y-H.,Yuan T-H.,Wang J-S., Chen H-C., Hwang Y-H., Lee C-H., Cheng T-J.. Cardiopulmonary toxicity of pulmonary exposure to occupationally-relevant zinc oxide nanoparticles. . Nanotoxicology .2014

109. 2014 Huang, Y-L.,Chen, H-W.,Han, B-C.,Liu, C-W.,Chuang, H-C.,Lin, L-Y., Chuang, K-J.. Personal exposure to household particulate matter, household activities and heart rate variability among housewives. . PLoS One .2014 ;(9):e89969

110. 2014 Chang C-C,Chuang H-C,Lin C-L,Sung F-C,Chang Y-J,Hsu, C-Y., Chiang, L-L.. High incidence of stroke in young females with sleep apnea syndrome . Sleep Medicine .2014 ;(15):410-414

111. 2014 Hung W-Y.,Yu M-C.,Chiang Y-C.,Chang J-H.,Chiang C-Y.,Chang C-C., Chuang H-C., Bai K-J.. Serum Concentration of Cycloserine and Outcome of Multidrug-Resistant Tuberculosis in Northern Taiwan . The International Journal of Tuberculosis and Lung Disease .2014 ;(18):601-606

112. 2014 Lee K-Y.,Wong C.,Chuang K-J.,Bien M-Y.,Cao J-J.,Han Y-M., Tian L-W., Chang C-C., Feng P-H., Ho K-F.*, Chuang H-C.*. Methionine oxidation in albumin by fine haze particulate matter: an in vitro and in vivo study . Journal of Hazardous Materials .2014 ;(274):384-391

113. 2014 Chang C-C.,Chuang H-C.,Lee C-N.,Hung W-Y.,Wang H-W.. Erlotinib: Lacking of Cholinergic Effects on Tracheal Smooth Muscle . Journal of Experimental and Clinical Medicine .2014 ;(6):98-101

114. 2014 Lee K-Y.,Liu W-T.,Kuo H-P.,Wang C-H.,Chuang H-C.,Chen T-T., Ho S-C.*, Hsu M-F., Chuang K-J.*. Air pollution exposure and osteoporosis among retired workers with chronic obstructive pulmonary disease. . Occupational Medicine and Health Affairs .2014 ;(2):100016

115. 2014 Pan C-H.,Liu W-T.,Bien M-Y.,Lin I-C.,Hsiao T-C.,Ma C-M., Lai C-H., Chen M-C., Chuang K-J.*#, Chuang H-C.*#.. Effects of size and surface of zinc oxide and aluminium-doped zinc oxide nanoparticles on cell viability inferred by proteomic analyses. . International Journal of Nanomedicine .2014 ;(9):3631-3643

116. 2014 Liu W-T.,Bien M-Y.,Chuang K-J.,Chang T-Y.,Jones T.,BéruBé K., Lalev G., Tsai D-H., Chuang H-C.*,#, Cheng T-J. *,#. Physicochemical and biological characterisation of single-walled and double-walled carbon nanotubes in biological media . Journal of Hazardous Materials .2014 ;(280):216-225

117. 2014 Xiao Z.,Shao L.*,Zhang N.,Wang J.,Chuang H-C.,Deng Z., Wang Z., BéruBé K.. A toxicological study of inhalable particulates in an industrial region of Lanzhou City, northwestern China: Results from plasmid scission assay. . Aeolian Research .2014 ;(14):25-34

118. 2013 Chuang HC,Hsueh TW,Chang CC,Hwang JS,Chuang KJ,Yan YH, Cheng TJ.. Nickel-regulated heart rate variability: The roles of oxidative stress and inflammation. . Toxicol Appl Pharmacol .2013 ;(266):298-306

119. 2013 Chuang KJ,Chen HW,Liu IJ,Chuang HC,Lin LY. The effect of essential oil on heart rate and blood pressure among solus por aqua workers. . Eur J Prev Cardiol .2013

120. 2013 Chuang HC,Berube K,Lung SC,Bai KJ,Jones T. Investigation into the oxidative potential generated by the formation of particulate matter from incense combustion. . J Hazard Mater .2013 ;(244):142-150

121. 2013 Chuang HC,Cheng YL,Lei YC,Chang HH,Cheng TJ. Protective effects of pulmonary epithelial lining fluid on oxidative stress and DNA single-strand breaks caused by ultrafine carbon black, ferrous sulphate and organic extract of diesel exhaust particles. . Toxicol Appl Pharmacol .2013 ;(266):329-334

122. 2013 Chuang HC,Lin LY,Hsu YW,Ma CM,Chuang KJ. In-car particles and cardiovascular health: An air conditioning-based intervention study . Science of the Total Environment .2013 ;(452-45):309-313

123. 2013 Chuang H-C,Jones T,Chen T-T,BeruBe K. Cytotoxic effects of incense particles in relation to oxidative stress, the cell cycle and F-actin assembly . Toxicology Letters .2013 ;(220):229-237

124. 2013 Lin L-Y,Liu I-J,Chuang H-C,Lin H-Y,Chuang K-J. Size and composition effects of household particles on inflammation and endothelial dysfunction of human coronary artery endothelial cells . Atmospheric Environment .2013 ;(77):490-495

125. 2013 Lin LY,Chuang HC,Liu IJ,Chen HW,Chuang KJ. Reducing indoor air pollution by air conditioning is associated with improvements in cardiovascular health among the general population. . Sci Total Environ .2013 ;(463-46):176-181

126. 2013 Su C-L.,Chen T-T.,Chang C-C.,Chuang K-J.,Wu C-K.,Liu, W-T., Ho, KF., Lee, KY., Ho, S-C., Tseng, H-E., Chuang, H-C., Cheng, T-J.. Comparative proteomics of inhaled silver nanoparticle in healthy and allergen provocation mice. . International Journal of Nanomedicine .2013 ;(8):2783-2799

127. 2013 Chuang K-J.,Chuang H-C.,Lin L-Y.. Indoor Air Pollution, Nighttime Heart Rate Variability and Coffee Consumption among Convenient Store Workers. . PLoS One .2013 ;(8):e63320

128. 2013 Chuang H-C.,Hsiao T-C.,Wu C-K.,Chang H-H.,Lee C-H.,Chang C-C., Cheng T-J.. Allergenicity and toxicology of inhaled silver nanoparticles in allergen-provocation mice models. . International Journal of Nanomedicine .2013 ;(8):4495-4506

129. 2013 Chiang L-L.,Chen H-C.,Lee C-N.,Chuang K-J.,Chen T-T.,Yeh C-T., Wang L-S., Lee W-H., Lin L-Y., Tseng H-E., Chuang H-C.. Serum protein oxidation by diesel exhaust particles: effects on oxidative stress and inflammatory response in vitro. . Chemico-Biological Interactions .2013 ;(206):385-393

130. 2013 Chen T-T.,Chuang K-J.,Chiang L-L.,Chen C-C.,Yeh C-T.,Wang L-S., Gregory C., Jones T., BéruBé K., Lee C-N., Chuang H-C., Cheng T-J.. Characterization of the interactions between protein and carbon black. . Journal of Hazardous Materials .2013 ;(264):127-135

131. 2012 Reche C,Moreno T,Amato F,Viana M,van Drooge BL,Chuang HC, Berube K, Jones T, Alastuey A, Querol X. A multidisciplinary approach to characterise exposure risk and toxicological effects of PM₁₀ and PM₂.₅ samples in urban environments. . Ecotoxicol Environ Saf .2012 ;(78):327-335

132. 2012 Chuang HC,Fan CW,Chen KY,Chang-Chien GP,Chan CC. Vasoactive alteration and inflammation induced by polycyclic aromatic hydrocarbons and trace metals of vehicle exhaust particles. . Toxicol Lett .2012 ;(214):131-136

133. 2012 Chuang HC,Jones T,BeruBeK. Combustion particles emitted during church services: implications for human respiratory health. . Environ Int .2012 ;(40):137-142

134. 2011 Chuang HC,Jones TP,Lung SC,BeruBe KA. Soot-driven reactive oxygen species formation from incense burning. . Sci Total Environ .2011 ;(409):4781-4787

135. 2011 Chuang HC,Jones T,Chen Y,Bell J,Wenger J,BéruBé K. Characterisation of airborne particles and associated organic components produced from incense burning . Analytical and Bioanalytical Chemistry .2011 ;(401):3095-102


1. 2010 Chuang H-C.,Wenger J,Jones T,BeruBe K. Characterisation of the gaseous and particulate oxygenated derivate products from incense burning . EUROCHAP-2 .2010


1. 2019 Chuang H-C.. Oxidative stress in Lung Diseases: Oxidative Stress in Environmental Lung Diseases . Springer Nature .2019 ;(1):293-308

研究計畫

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109 探討ITIH4經由Yap/Taz路徑調控急性呼吸窘迫症候群之第二型肺泡上皮細胞老化的角色
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108 職業駕駛之睡眠呼吸障礙與職業災害評估分析
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107 加強血基質氧化酶的基因與蛋白質表現是3,6-Dithiopomalidomide對腦創傷所引發急性肺損傷的保護機制之一
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107 The role of HMGB1 on lung injury and permeability in LPS and mechanical stretch cell models
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107 驗證人類間質幹細胞於Bleomycin誘導肺纖維化動物模式之功效
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107 實驗探討人類臍帶間質幹細胞對脂多醣誘導急性呼吸窘迫症候群動物模式的治療效果評估研究計畫
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107 即時移動污染源自體排放超細懸浮微粒之車載毒性測試平台建立與應用評估(II)
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106 實驗探討人類臍帶間質幹細胞對香菸誘導慢性阻塞性肺病動物模式的治療效果評估
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106 粒狀空氣污染物對於腦部功能變化與神經退化疾病之探索研究(2/2)
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103 慢性阻塞性肺病病患使用類固醇藥物易感受性下降相關性之探討:組蛋白去乙醯酶與細胞自噬功能所扮演的角色
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103 粒狀空氣污染物所產生的氧化壓力對慢性阻塞性肺疾病患者的泛素-蛋白酉每平衡系統之影響:探討氧化壓力,異常發炎以及蛋白質氧化之關係
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102 以蛋白質體學探討粒狀空氣污染物對肺結核引起肺積水樣本之生物指標與相關性之評估
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